This is what worked for me on level 15:
Fill in all tiny yellows (3-in-a-row), then continue doing yellow 3-in-a-row to build up to hourglass bonus. Turn all the jewels in the top two rows to red except for 6 in other colors in between to prevent any matches. Make the non-red jewels to be one click away from red. Then use hourglass bonus to turn the non-red to red. The hourglass gives you 5 free clicks without triggering matching, and the 6th will trigger the match. Doing it this way will give you two large reds at once. Repeat this method, though the 2nd & 3rd times you will get one large red and one medium red. Then as you fill in the rest of the jewels, make sure you build up to an "jewel sack" bonus (refills the board) first before filling more jewels. Continue filling-in all 4-in-a rows (white, pink, and yellow), then the rest of the 3-in-a-rows. It took a while! Great game, though!